The US Food and Drug Authority (FDA) has recently approved the use of a new drug for the treatment of influenza in October 2018, The drug called Baloxavir Marboxil (Xofluza) combats the two types of influenza that affect humans, influenza A and B.
Baloxavir Marboxil functions differently compared to drugs that are available in retail pharmacies in New York City, New York. This includes Oseltamivir (Tamiflu), Zanamivir (Relenza), and Peramivir (Rapivab), the usual flu medication. These older drugs limit the virus by blocking a certain viral enzyme called neuraminidase. On the other hand, Baloxavir inhibits a subunit of the viral polymerase, the enzyme responsible for influenza virus duplication.
In other words, this newly developed drug interferes with the flu virus’s ability to replicate itself while the older drugs only interfere with the flu virus’s ability to spread within the body.
This unique structure of action means that baloxavir is probably effective against strains of influenza A that resistant to oseltamivir, the drug widely used for the treatment of influenza. It might also be active against strains of avian influenza (“bird flu”).
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